The wrong drug.

Adverse events in anaesthesia: the wrong drug.

The first general anaesthetics resulted from the action of one drug, either ether or chloroform. Today, general anaesthetics are usually complex "cocktails" and it is not uncommon for several different drugs to be given. Each of these has a distinct, predictable pharmacological action. Thus, when an unpredicted reaction occurs shortly after the injection of a drug, one possible explanation is t...

Bevacizumab (Avastin) for retinopathy of prematurity: wrong dose, wrong drug, or both?

I nterest in and controversy over the use of bevacizumab (Avastin; Genentech/Roche, South San Francisco, CA) for the treatment of retinopathy of prematurity (ROP) have increased dramatically after the Bevacizumab Eliminates the Angiogenic Threat of Retinopathy of Prematurity (BEAT-ROP) study. Off-label bevacizumab has been used extensively for age-related macular degeneration (AMD) for more tha...

Thalidomide in small cell lung cancer: wrong drug or wrong disease?

Wrong-side/wrong-site, wrong-procedure, and wrong-patient adverse events: Are they preventable?

HYPOTHESIS Wrong-side/wrong-site, wrong-procedure, and wrong-patient adverse events (WSPEs) are devastating, unacceptable, and often result in litigation, but their frequency and root causes are unknown. Wrong-side/wrong-site, wrong-procedure, and wrong-patient events are likely more common than realized, with little evidence that current prevention practice is adequate. DESIGN Analysis of se...

Inside the Wrong Body